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Title: | Synthesis of Quinazolinones, Imidazo[1,2-c]quinazolines and Imidazo[4,5-c]quinolines through Tandem Reductive Amination of Aryl Halides and Oxidative Amination of C(sp3)–H Bonds |
Authors: | Kumar, Indresh |
Keywords: | Chemistry Synthesis Quinazolinones Aryl Halides Oxidative Amination |
Issue Date: | 3-Nov-2016 |
Publisher: | Wiley |
Abstract: | The synthesis of quinazolinones, imidazo[1,2-c]quinazolines and imidazo[4,5-c]quinolones has been achieved through a multicomponent copper-catalyzed reaction using easily available sodium azide as a nitrogen source, and DMA (N,N-dimethylacetamide) as a one-carbon source. N-Fused heterocycles were obtained in good to excellent yields, and the reaction is suitable for gram-scale synthesis. |
URI: | https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.201601329 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3167 |
Appears in Collections: | Department of Chemistry |
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