Microwave assisted aminocatalyzed [3 + 2] annulation between α-iminonitriles and succinaldehyde: synthesis of pyrrole-3-methanols and related polycyclic ring systems

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DC Field	Value	Language
dc.contributor.author	Kumar, Indresh	-
dc.date.accessioned	2021-10-27T04:27:43Z	-
dc.date.available	2021-10-27T04:27:43Z	-
dc.date.issued	2016	-
dc.identifier.uri	https://pubs.rsc.org/en/content/articlelanding/2016/ra/c6ra06831f	-
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3169	-
dc.description.abstract	A quick and highly efficient method for the synthesis of substituted pyrrole-3-methanols from α-iminonitriles and succinaldehyde under microwave irradiation is reported. This one-pot method involves aminocatalyzed direct Mannich reaction-cyclization-dehydrocyanation followed by NaBH4 reduction sequence in good yields (up to 75%). Further applications of this method are demonstrated through the rapid synthesis of polycyclic heterocycles such as pyrrolo-dihydrochromene and pyrrolo-dihydroquinoline compounds.	en_US
dc.language.iso	en	en_US
dc.publisher	RSC	en_US
dc.subject	Chemistry	en_US
dc.subject	Microwave	en_US
dc.subject	Aminocatalyzed [3 + 2]	en_US
dc.subject	Pyrrole-3-methanols	en_US
dc.title	Microwave assisted aminocatalyzed [3 + 2] annulation between α-iminonitriles and succinaldehyde: synthesis of pyrrole-3-methanols and related polycyclic ring systems	en_US
dc.type	Article	en_US
Appears in Collections:	Department of Chemistry

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