Fluorescent glutamine and asparagine as promising probes for chemical biology

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DC Field	Value	Language
dc.contributor.author	Sakhuja, Rajeev	-
dc.contributor.author	Jha, Prabhat Nath	-
dc.contributor.author	Kumar, Dalip	-
dc.date.accessioned	2021-11-11T10:57:49Z	-
dc.date.available	2021-11-11T10:57:49Z	-
dc.date.issued	2021	-
dc.identifier.uri	https://pubs.rsc.org/en/content/articlelanding/2021/ob/d1ob01029h	-
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3340	-
dc.description.abstract	Fluorescent probes have become valuable tools in chemical biology, providing interesting inferences for unfolding the complexities of natural biochemical processes. In this study, we report the synthesis and characterization of fluorescent labelled glutamine (Gln) and asparagine (Asn) derivatives via traceless Staudinger ligation, which exhibited high fluorescence quantum yields, excellent photostabilities and emission of blue fluorescence in the visible region. The successful permeation of these fluorescent amino acids into cellular components proved their potential as fluorescent probes for chemical biology.	en_US
dc.language.iso	en	en_US
dc.publisher	RSC	en_US
dc.subject	Chemistry	en_US
dc.subject	Fluorescent	en_US
dc.subject	Glutamine	en_US
dc.subject	Asparagine	en_US
dc.title	Fluorescent glutamine and asparagine as promising probes for chemical biology	en_US
dc.type	Article	en_US
Appears in Collections:	Department of Chemistry

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