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Please use this identifier to cite or link to this item: http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/3358
Title: Aziridine-Mediated Ligation at Phenylalanine and Tryptophan Sites
Authors: Sakhuja, Rajeev
Bajaj, Kiran
Keywords: Chemistry
Aziridine-Mediated
Phenylalanine
Tryptophan
Issue Date: 23-May-2017
Publisher: Wiley
Abstract: An efficient approach towards peptide synthesis that allows easy access to variety of small peptides via one-pot aziridine-mediated ligation/desulfurization strategy has been described. The protocol afforded a library of phenylalanine- and tryptophan-containing α-peptides in good yields by regioselective ring-opening of aziridine-3-aryl-2-carboxylates with peptide thioacids, followed by desulfurization.
URI: https://onlinelibrary.wiley.com/doi/10.1002/asia.201700538
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3358
Appears in Collections:Department of Chemistry

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