DSpace logo

Please use this identifier to cite or link to this item: http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/3384
Title: The Chemistry of N-Hydroxyamidoximes, N-Aminoamidoximes, and Hydrazidines
Authors: Sakhuja, Rajeev
Keywords: Chemistry
Salts
Anions
Reaction products
Issue Date: 27-Feb-2012
Publisher: ACS
Abstract: N-Hydroxyamidoximes, N-aminoamidoximes, and hydrazidines belong to a class of compounds with the general formula RC═NX(NHY) where X = OH or NH2, Y = OH or NH2, and R is a linear side chain, carbocycle residue, or heterocycle residue. Their structures are similar to those of amidoximes and amidrazones, but they possess very different synthetic utility and pharmacological properties. There are several reviews published on the synthetic and biological applications of amidrazones and amidoximes. (1-8) However, a comprehensive review on the preparative methods, synthetic utility, and biological applications is missing for this class of compounds thus far. We now attempt to readdress the situation by providing a detailed compilation on the chemistry of N-hydroxyamidoximes, N-aminoamidoximes, and hydrazidines in terms of the structure, preparative methods, reactivity, and biological applications.
URI: https://pubs.acs.org/doi/10.1021/cr200076q
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3384
Appears in Collections:Department of Chemistry

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.