Syntheses of hydrazino peptides and conjugates

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DC Field	Value	Language
dc.contributor.author	Bajaj, Kiran	-
dc.date.accessioned	2021-11-11T11:23:18Z	-
dc.date.available	2021-11-11T11:23:18Z	-
dc.date.issued	2013-07	-
dc.identifier.uri	https://augusta.pure.elsevier.com/en/publications/syntheses-of-hydrazino-peptides-and-conjugates	-
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3501	-
dc.description.abstract	(α-Benzyloxycarbonyl-aminoacyl)benzotriazolides (Cbz = benzyloxycarbonyl) underwent a coupling reaction with α-hydrazino acids under microwave irradiation to form hybrid hydrazino dipeptides (42-71 %). Chiral acylations of β-N-Cbz-α-hydrazino acylbenzotriazolides were successfully carried out with N-, S-, O-, and C-nucleophiles in yields of 49-88 %. Benzyloxycarbonyl-protected hybrid hydrazino dipeptides and benzyloxycarbonyl-protected hydrazino aminoacyl conjugates with N-, S-, O-, and C-nucleophiles were prepared by using benzotriazole methodology.	en_US
dc.language.iso	en	en_US
dc.publisher	Elsiever	en_US
dc.subject	Chemistry	en_US
dc.subject	Acylation	en_US
dc.subject	Conjugates	en_US
dc.subject	Microwave chemistry	en_US
dc.subject	Peptides	en_US
dc.subject	Synthetic methods	en_US
dc.title	Syntheses of hydrazino peptides and conjugates	en_US
dc.type	Article	en_US
Appears in Collections:	Department of Chemistry

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