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http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/3519| Title: | Newer Substituted Benzoxazepinylquinazolinones as Potent Antipsychotic and Anticonvulsant Agents |
| Authors: | Bajaj, Kiran |
| Keywords: | Chemistry Benzoxazepinylquinazolinones Acute toxicity studies Anticonvulsant activity Hypnotic - activity |
| Issue Date: | 2003 |
| Publisher: | Thieme |
| Abstract: | 3-Amino-[2’-substitutedaryl-3’-substitutedarylaminomethylene-2’,3’-dihydro-1’,5’-benzoxazepin-4’-yl]-2-methylquinazolin-4(3H)-ones 11−18 and 3-amino-[2’-substituted aryl-3’-substitutedaryl-azo-2’,3’-dihydro-1’,5’-benzoxazepin-4’-yl]-2-methyl-quinazolin-4(3H)-ones 19− 26 were synthesized from 3-amino-[2’-substitutedaryl-2’,3’-dihydro-1’,5’-benzoxazepin-4’-yl]-2-methyl-quinazolin-4(3H)-ones 7−10 by Mannich’s reaction and by diazotisation, respectively, on the 3rd position of the benzoxazepine ring of the compounds 7−10. The newly synthesized compounds showed potent antipsychotic and anticonvulsant activities. |
| URI: | https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0031-1297137 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3519 |
| Appears in Collections: | Department of Chemistry |
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