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Results 31-40 of 53 (Search time: 0.003 seconds).
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Issue Date
Title
Author(s)
2020-12
Targeting a conserved pocket (n-octyl-β-D–glucoside) on the dengue virus envelope protein by small bioactive molecule inhibitors
Murugesan, Sankaranarayanan
2022-06
Liposomes: An emerging carrier for targeting Alzheimer's and Parkinson's diseases
Murugesan, Sankaranarayanan
2020-10
In-vivo and in-silico toxicity studies of daidzein: an isoflavone from soy
Murugesan, Sankaranarayanan
2022-01
Design, synthesis and structure–activity relationship studies of novel spirochromanone hydrochloride analogs as anticancer agents
Murugesan, Sankaranarayanan
2022-06
Design, synthesis and evaluation of novel phenanthridine triazole analogs as potential antileishmanial agents
Murugesan, Sankaranarayanan
2022
Graph theoretical network analysis, in silico exploration, and validation of bioactive compounds from Cynodon dactylon as potential neuroprotective agents against α-synuclein
Murugesan, Sankaranarayanan
2020
Leishmaniasis is the most widespread pathogenic disease in several countries. Currently, no effective vaccines are available, and the control of Leishmaniasis primarily relies on decade-old chemotherapy. The treatment for the Leishmaniasis is not up to the mark. Current therapy for Leishmaniasis is ancient and requires hospitalization for the administration. These medications are also highly toxic and resistant. β-carboline, a natural indole containing alkaloid, holds a vital position in the field of medicinal chemistry with a diversified pharmacological action. The current review focuses mainly on the anti-leishmanial effects of β-carboline analogs and their synthetic strategies, structural activity relationship studies (SAR). The past ten years alterations unveiled by β-carboline analogs present in phytoconstituents and various derivatives of synthesized analogs with the mechanism of action were briefly shortlisted and illustrated
Murugesan, Sankaranarayanan
2020-09
Review article| Volume 6, ISSUE 9, e04916, September 2020 PDF [2 MB] Figures Save Share Reprints Request Recent evolution on synthesis strategies and anti-leishmanial activity of β-carboline derivatives – An update
Murugesan, Sankaranarayanan
2020-11
Druggable targets of SARS-CoV-2 and treatment opportunities for COVID-19
Murugesan, Sankaranarayanan
2020-07
Design, synthesis, in silico studies, and evaluation of novel chalcones and their pyrazoline derivatives for antibacterial and antitubercular activities
Murugesan, Sankaranarayanan
Discover
Author
3
Deepa, P. R.
2
Sharma, Pankaj Kumar
1
Chakraborty, Shamik
1
Sah, Ajay Kumar
Subject
50
Pharmacy
13
Molecular docking
7
COVID-19
6
Molecular dynamics
6
SARS-CoV-2
6
Synthesis
5
Drug repurposing
4
ADMET
4
Leishmaniasis
3
Anti-tubercular
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