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Results 41-50 of 56 (Search time: 0.002 seconds).
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Issue DateTitleAuthor(s)
2022-06Design, synthesis and evaluation of novel phenanthridine triazole analogs as potential antileishmanial agentsMurugesan, Sankaranarayanan
2022Graph theoretical network analysis, in silico exploration, and validation of bioactive compounds from Cynodon dactylon as potential neuroprotective agents against α-synucleinMurugesan, Sankaranarayanan
2020Leishmaniasis is the most widespread pathogenic disease in several countries. Currently, no effective vaccines are available, and the control of Leishmaniasis primarily relies on decade-old chemotherapy. The treatment for the Leishmaniasis is not up to the mark. Current therapy for Leishmaniasis is ancient and requires hospitalization for the administration. These medications are also highly toxic and resistant. β-carboline, a natural indole containing alkaloid, holds a vital position in the field of medicinal chemistry with a diversified pharmacological action. The current review focuses mainly on the anti-leishmanial effects of β-carboline analogs and their synthetic strategies, structural activity relationship studies (SAR). The past ten years alterations unveiled by β-carboline analogs present in phytoconstituents and various derivatives of synthesized analogs with the mechanism of action were briefly shortlisted and illustratedMurugesan, Sankaranarayanan
2020-09Review article| Volume 6, ISSUE 9, e04916, September 2020 PDF [2 MB] Figures Save Share Reprints Request Recent evolution on synthesis strategies and anti-leishmanial activity of β-carboline derivatives – An updateMurugesan, Sankaranarayanan
2020-11Druggable targets of SARS-CoV-2 and treatment opportunities for COVID-19Murugesan, Sankaranarayanan
2020-07Design, synthesis, in silico studies, and evaluation of novel chalcones and their pyrazoline derivatives for antibacterial and antitubercular activitiesMurugesan, Sankaranarayanan
2020Seeking potent anti-tubercular agents: design and synthesis of substituted-N-(6-(4-(pyrazine-2-carbonyl)piperazine/homopiperazine-1-yl)pyridin-3-yl)benzamide derivatives as anti-tubercular agentsMurugesan, Sankaranarayanan
2020-10Synthesis, biological evaluation, molecular docking, molecular dynamics and DFT studies of quinoline-fluoroproline amide hybridsMurugesan, Sankaranarayanan
2020-07Discovery of 1,2,3-triazole based quinoxaline-1,4-di-N-oxide derivatives as potential anti-tubercular agentsMurugesan, Sankaranarayanan
2020Sequential multicomponent catalytic synthesis of pyrrole-3-carboxaldehydes: Evaluation for antibacterial and antifungal activities along with docking studiesMurugesan, Sankaranarayanan