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Design and Fabrication Issues in Affinity Cantilevers for bioMEMS Applications

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dc.contributor.author Rao, V. Ramgopal
dc.date.accessioned 2023-10-30T09:11:10Z
dc.date.available 2023-10-30T09:11:10Z
dc.date.issued 2006-12
dc.identifier.uri https://ieeexplore.ieee.org/abstract/document/4020272
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/12724
dc.description.abstract Microfabricated cantilevers are widely used for biomedical sensing applications. In this paper, for the first time, design guidelines have been provided for composite polymeric microcantilevers with embedded piezoresistors. Optimization guidelines have been provided from the point of reducing their stiffness and to increase their deflection and the <formula formulatype="inline"><tex>ΔR/R</tex></formula> response. Choice of the piezoresistive material and the location of this layer with respect to the neutral axis are shown to impact the stiffness and <formula formulatype="inline"><tex>ΔR/R</tex> </formula> of a microcantilever. Differences in the behavior of <formula formulatype="inline"> <tex>ΔR/R</tex></formula> and deflection, when surface stresses are applied to polymer based microcantilevers and oxide/nitride based ones, are brought out. We also show that it is essential to have the immobilization layer and the piezoresistor on the same side of the neutral axis particularly when these microcantivelers are used for sensing small surface stresses in the order of a few mN/m, typical of many molecular markers used in biomedical applications. en_US
dc.language.iso en en_US
dc.publisher IEEE en_US
dc.subject EEE en_US
dc.subject Affinity cantilevers en_US
dc.subject Antibody immobilization en_US
dc.subject Biomems en_US
dc.subject Hotwire CVD (HWCVD) en_US
dc.subject Polymeric cantilevers en_US
dc.title Design and Fabrication Issues in Affinity Cantilevers for bioMEMS Applications en_US
dc.type Article en_US


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