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Neuropharmacological evaluation of a novel 5-HT3 receptor antagonist (6g) on chronic unpredictable mild stress-induced changes in behavioural and brain oxidative stress parameters in mice

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dc.contributor.author Mahesh, R.
dc.date.accessioned 2023-11-18T06:36:18Z
dc.date.available 2023-11-18T06:36:18Z
dc.date.issued 2014-03
dc.identifier.uri https://www.ijp-online.com/article.asp?issn=0253-7613;year=2014;volume=46;issue=2;spage=191;epage=196;aulast=Bhatt
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13165
dc.description.abstract The aim of the study was to evaluate a novel 5 HT3 receptor antagonist (6g) on chronic stress induced changes in behavioural and brain oxidative stress parameter in mice. A complicated relationship exists among stressful stimuli, body's reaction to stress and the onset of clinical depression. Chronic unpredictable stressors can produce a situation similar to human depression, and such animal models can be used for the preclinical evaluation of antidepressants. en_US
dc.language.iso en en_US
dc.publisher Wolters Kluwer en_US
dc.subject Pharmacy en_US
dc.subject 5-HT3 receptor antagonist en_US
dc.subject Chronic unpredictable mild stress (CUMS) en_US
dc.subject Depression en_US
dc.subject Oxidative stress en_US
dc.title Neuropharmacological evaluation of a novel 5-HT3 receptor antagonist (6g) on chronic unpredictable mild stress-induced changes in behavioural and brain oxidative stress parameters in mice en_US
dc.type Article en_US


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