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Etazolate, a phosphodiesterase-4 enzyme inhibitor produces antidepressant-like effects by blocking the behavioral, biochemical, neurobiological deficits and histological abnormalities in hippocampus region caused by olfactory bulbectomy

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dc.contributor.author Mahesh, R.
dc.date.accessioned 2023-11-20T04:03:44Z
dc.date.available 2023-11-20T04:03:44Z
dc.date.issued 2014-08
dc.identifier.uri https://link.springer.com/article/10.1007/s00213-014-3705-0
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13168
dc.description.abstract Olfactory bulbectomy (OBX) is a widely used model for antidepressant screening and known to induce neurodegeneration in several brain areas. Our earlier studies demonstrated that etazolate produced antidepressant-like effects in behavioral despair models of depression; however, the potential role of etazolate on behavior and morphological changes in the hippocampus region along with its underlying mechanism(s) following OBX has not been adequately addressed. en_US
dc.language.iso en en_US
dc.publisher Springer en_US
dc.subject Olfactory bulbectomy (OBX) en_US
dc.subject Phosphodiesterase-4 en_US
dc.subject Etazolate en_US
dc.title Etazolate, a phosphodiesterase-4 enzyme inhibitor produces antidepressant-like effects by blocking the behavioral, biochemical, neurobiological deficits and histological abnormalities in hippocampus region caused by olfactory bulbectomy en_US
dc.type Article en_US


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