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1,2,3,4-Tetrahydroisoquinoline (THIQ) as privileged scaffold for anticancer de novo drug design

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dc.contributor.author Murugesan, Sankaranarayanan
dc.date.accessioned 2023-12-11T10:42:20Z
dc.date.available 2023-12-11T10:42:20Z
dc.date.issued 2021-04
dc.identifier.uri https://www.tandfonline.com/doi/full/10.1080/17460441.2021.1916464
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13344
dc.description.abstract Cancer is a dreadful disorder that is emerging as one of the leading causes of mortality across the globe. The complex tumor environment, supplemented with drawbacks of the existing drugs, has made it a global health concern. The Tetrahydroisoquinoline (THIQ) ring holds an important position in medicinal chemistry due to its wide range of pharmacological properties. Several THIQ based natural products have been previously explored for their antitumor properties, making it a vital scaffold for anticancer drug design. en_US
dc.language.iso en en_US
dc.publisher Taylor & Francis en_US
dc.subject Pharmacy en_US
dc.subject Tumor en_US
dc.subject Benzo piperidine en_US
dc.subject 3, 4-dihydro-1H-isoquinoline en_US
dc.subject 1, 2, 3, 4-tetrahydro-2-azanaphthalene en_US
dc.subject Synthesis en_US
dc.subject Epigenetics en_US
dc.title 1,2,3,4-Tetrahydroisoquinoline (THIQ) as privileged scaffold for anticancer de novo drug design en_US
dc.type Article en_US


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