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Protective effect and mechanism of Ginkgo biloba extract-EGb 761 on STZ-induced diabetic cardiomyopathy in rats

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dc.contributor.author Taliyan, Rajeev
dc.date.accessioned 2023-12-12T09:31:45Z
dc.date.available 2023-12-12T09:31:45Z
dc.date.issued 2014
dc.identifier.uri https://phcog.com/article/view/2014/10/38/172-178
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13367
dc.description.abstract Diabetes mellitus (DM) is a complex metabolic disorder which leads to development of various long-term complications including cardiomyopathy. Oxidative stress due to hyperglycemia plays a key role in the development and progression of diabetic cardiomyopathy (DC). Oxidative stress causes the opening of mitochondrial permeability transition pore (mPTP) eventually leading to myocardium dysfunction. The Ginkgo biloba extract (EGb 761) has antioxidant and mitochondrial membrane potential stabilizing property. Therefore, this study was designed to evaluate the effect of EGb 761 and its possible mechanism of action in DC. en_US
dc.language.iso en en_US
dc.publisher Pharmacognosy Magazine en_US
dc.subject Pharmacy en_US
dc.subject Cardioprotective en_US
dc.subject Diabetes mellitus en_US
dc.subject EGb 761 en_US
dc.subject mPTP channel en_US
dc.subject Oxidative stress en_US
dc.title Protective effect and mechanism of Ginkgo biloba extract-EGb 761 on STZ-induced diabetic cardiomyopathy in rats en_US
dc.type Article en_US


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