| dc.contributor.author |
Taliyan, Rajeev |
|
| dc.date.accessioned |
2023-12-12T10:52:11Z |
|
| dc.date.available |
2023-12-12T10:52:11Z |
|
| dc.date.issued |
2015-08 |
|
| dc.identifier.uri |
https://www.degruyter.com/document/doi/10.1515/jbcpp-2015-0021/html |
|
| dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13377 |
|
| dc.description.abstract |
Hydroxy safflor yellow A (HSYA) has been translated clinically for cardiovascular diseases. HSYA is also greatly acknowledged for its protective effects against cerebral ischemic-reperfusion (I/R) injury. Although the precise mechanism of cerebral I/R injury is not fully understood, oxygen-derived free radicals and mitochondrial permeability transition pore (mPTP) opening during I/R injury are widely recognized as an important contributor to neuronal injury. Thus, we speculated that the neuroprotective effects of HSYA against cerebral I/R injury may be associated with mPTP modulation. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
De Gruyter |
en_US |
| dc.subject |
Pharmacy |
en_US |
| dc.subject |
Carboxyatractyloside |
en_US |
| dc.subject |
Cerebral ischemic-reperfusion injury |
en_US |
| dc.subject |
Hydroxy safflor yellow A (HSYA) |
en_US |
| dc.subject |
Mitochondrial permeability transition pore (mPTP) |
en_US |
| dc.title |
Neuroprotective effect of hydroxy safflor yellow A against cerebral ischemia-reperfusion injury in rats: putative role of mPTP |
en_US |
| dc.type |
Article |
en_US |