| dc.contributor.author |
Gaikwad, Anil Bhanudas |
|
| dc.date.accessioned |
2023-12-18T11:59:10Z |
|
| dc.date.available |
2023-12-18T11:59:10Z |
|
| dc.date.issued |
2009-01 |
|
| dc.identifier.uri |
https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1038/sj.bjp.0707666 |
|
| dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13439 |
|
| dc.description.abstract |
Curcumin has been used to treat cancer, diabetes and other pathologies. However, little is known regarding its role in altering post-translational modifications of histone H3. A recent report suggests that acute hyperglycaemia induces a global down-regulation of gene expression in human tissues and epigenetic regulation of gene expression could be a novel mechanism underlying the pathological processes of hyperglycaemia. The present study was undertaken to examine changes in histone modification by curcumin treatment which prevents development of type I diabetic nephropathy. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
Wiley |
en_US |
| dc.subject |
Pharmacy |
en_US |
| dc.subject |
Diabetic nephropathy |
en_US |
| dc.subject |
Streptozotocin |
en_US |
| dc.subject |
Cancer |
en_US |
| dc.title |
Change in post-translational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocin-induced type I diabetic nephropathy |
en_US |
| dc.type |
Article |
en_US |