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Telmisartan and thiorphan combination treatment attenuates fibrosis and apoptosis in preventing diabetic cardiomyopathy

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dc.contributor.author Gaikwad, Anil Bhanudas
dc.date.accessioned 2023-12-19T09:32:15Z
dc.date.available 2023-12-19T09:32:15Z
dc.date.issued 2018-09
dc.identifier.uri https://academic.oup.com/cardiovascres/article/115/2/373/5090455?login=true
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13452
dc.description.abstract LCZ696, a first-generation dual angiotensin receptor-neprilysin inhibitor (ARNi), is effective in treating heart failure patients. However, the role of ARNis in treating diabetic cardiomyopathy is poorly understood. This study evaluates the efficacy of a novel combination of telmisartan [angiotensin receptor blocker (ARB)] and thiorphan [neprilysin inhibitor (NEPi)] in ameliorating diabetic cardiomyopathy while, at the same time, exploring the relevant underlying molecular mechanism(s). en_US
dc.language.iso en en_US
dc.publisher Oxford en_US
dc.subject Pharmacy en_US
dc.subject LCZ696, en_US
dc.subject Cardiomyopathy en_US
dc.subject Diabetic nephropathy en_US
dc.title Telmisartan and thiorphan combination treatment attenuates fibrosis and apoptosis in preventing diabetic cardiomyopathy en_US
dc.type Article en_US


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