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Cyproheptadine, a SET7/9 inhibitor, reduces hyperglycaemia-induced ER stress alleviating inflammation and fibrosis in renal tubular epithelial cells

Cyproheptadine, a SET7/9 inhibitor, reduces hyperglycaemia-induced ER stress alleviating inflammation and fibrosis in renal tubular epithelial cells

Gaikwad, Anil Bhanudas
URI: https://www.tandfonline.com/doi/abs/10.1080/13813455.2022.2105365
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13504
Date: 2022-08

Abstract:

Persistent hyperglycaemia increases SET7/9 expression and endoplasmic reticulum (ER) stress which causes inflammation, apoptosis, and fibrosis in renal tubular epithelial cells leading to diabetic kidney disease (DKD)

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