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P0527 Hyperglycemia-associated Acute Kidney Injury Increases the Susceptibility Towards Neurological Dysfunction: Role of Angiotensin Ii Type 2 Receptor and Angiotensin-converting Enzyme 2

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dc.contributor.author Gaikwad, Anil Bhanudas
dc.date.accessioned 2023-12-27T07:14:49Z
dc.date.available 2023-12-27T07:14:49Z
dc.date.issued 2020-06
dc.identifier.uri https://academic.oup.com/ndt/article/35/Supplement_3/gfaa142.P0527/5852684
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13532
dc.description.abstract In clinical settings, diabetics remain on higher risk of ischemic renal injury (IRI) than nondiabetic patients. In addition, IRI predisposes distant organs to dysfunction such as neurological impairments via activation of the pressor arm of renin-angiotensin system (RAS). In contrast, the role of depressor arm of RAS on IRI-associated neurological sequalae remains elusive. Hence, this study explored the role of angiotensin II type 2 receptor (AT2R) and angiotensin-converting enzyme 2 (ACE2) in IRI-associated neurological dysfunctions under nondiabetic (ND) and diabetes mellitus (DM) condition. en_US
dc.language.iso en en_US
dc.publisher OUP en_US
dc.subject Pharmacy en_US
dc.subject Cytokine storm en_US
dc.subject Ischemic renal injury (IRI) en_US
dc.subject Enzyme inhibition en_US
dc.title P0527 Hyperglycemia-associated Acute Kidney Injury Increases the Susceptibility Towards Neurological Dysfunction: Role of Angiotensin Ii Type 2 Receptor and Angiotensin-converting Enzyme 2 en_US
dc.type Article en_US


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