| dc.contributor.author |
Gaikwad, Anil Bhanudas |
|
| dc.date.accessioned |
2023-12-27T07:22:08Z |
|
| dc.date.available |
2023-12-27T07:22:08Z |
|
| dc.date.issued |
2015 |
|
| dc.identifier.uri |
https://pharmacy.nmims.edu/docs/hdac-article-04.pdf |
|
| dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13535 |
|
| dc.description.abstract |
Post translational modifications of histones play a significant role in regulation of physiological and
pathological processes in the body. Acetylation is one of the most important chromatin modifying
mechanisms being controlled by histone acetyl transferases and histone deacetylases. The histone
deacetylases (HDAC) are basically responsible for silencing of gene transcription. Cancer involves
silencing of a large number of genes. Inhibition of such gene silencing could possibly lead us to
alleviatin or control of cancer progression. Natural HDAC inhibitors, a highly researched topic thus
seems an attractive method to conquer the kingdom of cancer and thus prove to be the ‘bull’s eye’ like
target for cancer treatment |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
NMIMS |
en_US |
| dc.subject |
Pharmacy |
en_US |
| dc.subject |
Cancer |
en_US |
| dc.subject |
Epigenetics |
en_US |
| dc.subject |
Histone deacetylases (HDACs) |
en_US |
| dc.subject |
Natural HDAC inhibitors |
en_US |
| dc.title |
Natural HDAC Inhibitors: Nature’s Answer to the Cancer |
en_US |
| dc.type |
Article |
en_US |