| dc.contributor.author |
Paul, Atish Tulshiram |
|
| dc.date.accessioned |
2023-12-27T10:44:53Z |
|
| dc.date.available |
2023-12-27T10:44:53Z |
|
| dc.date.issued |
2010-08 |
|
| dc.identifier.uri |
https://www.sciencedirect.com/science/article/pii/S0944711310000334 |
|
| dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13539 |
|
| dc.description.abstract |
A series of Sarsapogenin and Diosgenin derived steroidal constituents (1-12), isolated from Solanum xanthocarpum and Asparagus racemosus were screened for their ability to induce cell death and apoptosis of colon carcinoma cells. The carbohydrate moieties linked to the steroid backbones were found to strongly influence cytotoxic activity and cell death mode (apoptosis or necrosis). Compound 10, from A. racemosus was found to be a potent inducer of apoptosis. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
Elsevier |
en_US |
| dc.subject |
Pharmacy |
en_US |
| dc.subject |
Anticancer activity |
en_US |
| dc.subject |
Apoptosis |
en_US |
| dc.subject |
Sarsapogenin and Diosgenin derived steroidal constituents |
en_US |
| dc.subject |
Glycoalkaloids |
en_US |
| dc.subject |
Solanum xanthocarpum |
en_US |
| dc.subject |
Asparagus racemosus |
en_US |
| dc.title |
Apoptosis inducing activity of steroidal constituents from Solanum xanthocarpum and Asparagus racemosus |
en_US |
| dc.type |
Article |
en_US |