| dc.contributor.author | Paul, Atish Tulshiram | |
| dc.date.accessioned | 2023-12-29T09:56:16Z | |
| dc.date.available | 2023-12-29T09:56:16Z | |
| dc.date.issued | 2007-11 | |
| dc.identifier.uri | https://pubs.acs.org/doi/full/10.1021/jm0706923 | |
| dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13551 | |
| dc.description.abstract | The target for the anti-inflammatory natural products like amentoflavone (2), which act by interfering with the proinflammatory cytokine pathway (e.g., TNF-α, IL-1β, and NO synthase), is not yet well-defined. Data obtained from docking, electronic, and surface analyses shed some light on steric and electronic complementarity of these molecules to p38 MAPK, thereby suggesting a possible mechanism by which they might reduce the production of proinflammatory cytokines. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | ACS | en_US |
| dc.subject | Pharmacy | en_US |
| dc.subject | Inhibitors | en_US |
| dc.subject | Ligands | en_US |
| dc.subject | Molecular interactions | en_US |
| dc.subject | Peptides and proteins | en_US |
| dc.title | Evaluation of Proinflammatory Cytokine Pathway Inhibitors for p38 MAPK Inhibitory Potential | en_US |
| dc.type | Article | en_US |
| Files | Size | Format | View |
|---|---|---|---|
|
There are no files associated with this item. |
|||