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Design and Synthesis of Echitamine-inspired Hybrid Analogues Containing Thiazolidinediones as Potential Pancreatic Lipase Inhibitors

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dc.contributor.author Paul, Atish Tulshiram
dc.date.accessioned 2024-01-02T04:51:34Z
dc.date.available 2024-01-02T04:51:34Z
dc.date.issued 2022-11
dc.identifier.uri https://www.ingentaconnect.com/content/ben/lddd/2022/00000019/00000011/art00003
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13590
dc.description.abstract Obesity is a multifactorial metabolic disease characterised by excessive accumulation of triglycerides. The prevalence and morbidity rates associated with obesity are increasing tremendously, posing a significant risk to society. Pancreatic lipase (PL) is a key enzyme responsible for the digestion of dietary triglycerides; hence its inhibition is considered an attractive target in obesity. en_US
dc.language.iso en en_US
dc.publisher Bentham Science en_US
dc.subject Pharmacy en_US
dc.subject Obesity en_US
dc.subject Enzyme inhibition en_US
dc.subject Fluorescence spectroscopy en_US
dc.subject Molecular docking en_US
dc.subject Pancreatic lipase en_US
dc.subject Thiazolidinediones (TZDs) en_US
dc.title Design and Synthesis of Echitamine-inspired Hybrid Analogues Containing Thiazolidinediones as Potential Pancreatic Lipase Inhibitors en_US
dc.type Article en_US


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