Abstract:
Coating a tablet provides different features to the dosage form. Pan coating is the traditional method for film, enteric, or sugar coating of tablets. The coating process is dependent upon the advances in the techniques, equipment, and material used for coating. Despite advancements in the rules for scale-up of the pan-coating process, the laboratory scale process possesses several gaps leading to differences in the results observed on large scale. The chapter describes the thermodynamic factors, pan and spray-related factors that affect the pan-coating process, and determines the quality of the product. The final section of the chapter explains the scale-up of the pan-coating process.