| dc.contributor.author |
Pandey, Murali Monohar |
|
| dc.date.accessioned |
2024-01-12T06:47:29Z |
|
| dc.date.available |
2024-01-12T06:47:29Z |
|
| dc.date.issued |
2017 |
|
| dc.identifier.uri |
https://www.eurekaselect.com/article/77973 |
|
| dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13838 |
|
| dc.description.abstract |
A new, simple, specific and sensitive reverse-phase liquid chromatographic method was developed and validated for the estimation of felodipine (FDP) in rabbit plasma using fluorescence detector.
Materials and Methods: Plasma standard were prepared using a simple and one-step protein precipitation method and 50 μ l of the standard solutions were injected into the column. The method was found to be linear in the concentration range of 10–1000 ng/ml. The developed bioanalytical method was validated as per standard guidelines. Validation study results demonstrated accuracy, precision, sensitivity and selectivity of the proposed method. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
Bentham Science |
en_US |
| dc.subject |
Pharmacy |
en_US |
| dc.subject |
Felodipine |
en_US |
| dc.subject |
Fluorescence detector |
en_US |
| dc.subject |
High-performance liquid chromatography |
en_US |
| dc.subject |
Rabbit plasma |
en_US |
| dc.subject |
Pharmacokinetic study |
en_US |
| dc.subject |
Oral tablet |
en_US |
| dc.title |
Development and Validation of a Simple High-Performance Liquid Chromatography Method for Estimation of Felodipine in Rabbit Plasma: Application to Pharmacokinetic Study |
en_US |
| dc.type |
Article |
en_US |