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Statistical mechanics of thermal denaturation of DNA oligomers

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dc.contributor.author Singh, Navin
dc.date.accessioned 2024-02-20T05:04:44Z
dc.date.available 2024-02-20T05:04:44Z
dc.date.issued 2003-08
dc.identifier.uri https://link.springer.com/article/10.1007/BF02708314
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/14361
dc.description.abstract Double stranded DNA chain is known to have non-trivial elasticity. We study the effect of this elasticity on the denaturation profile of DNA oligomer by constraining one base pair at one end of the oligomer to remain in unstretched (or intact) state. The effect of this constraint on the denaturation profile of the oligomer has been calculated using the Peyrard-Bishop Hamiltonian. The denaturation profile is found to be very different from the free (i.e. without the constraint) oligomer. We have also examined how this constraint affects the denaturation profile of the oligomer having a segment of defect sites located at different parts of the chain. en_US
dc.language.iso en en_US
dc.publisher Springer en_US
dc.subject Physics en_US
dc.subject DNA Chain en_US
dc.subject DNA oligomers en_US
dc.title Statistical mechanics of thermal denaturation of DNA oligomers en_US
dc.type Article en_US


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