dc.contributor.author | Kumar, Anil | |
dc.date.accessioned | 2024-09-10T09:23:25Z | |
dc.date.available | 2024-09-10T09:23:25Z | |
dc.date.issued | 2023-02 | |
dc.identifier.uri | https://pubs.acs.org/doi/10.1021/acs.joc.2c02719 | |
dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/15508 | |
dc.description.abstract | A facile and efficient synthetic method for the construction of C3-hydroxyalkylated imidazo[1,2-a]pyridines and indoles by a Zn(OTf)2-catalyzed Friedel–Crafts hydroxyalkylation of imidazo[1,2-a]pyridines and indoles with carbonyl compounds under mechanochemical conditions is reported. Good product selectivity, shorter reaction time, ambient reaction temperature, tolerance of a wide range of functional groups, broad substrate scope, moderate to good yield of products, and scalability are the salient features of the developed methodology. | en_US |
dc.language.iso | en | en_US |
dc.publisher | ACS | en_US |
dc.subject | Chemistry | en_US |
dc.subject | Chemical Reactions | en_US |
dc.subject | Ethyl groups | en_US |
dc.subject | Indoles | en_US |
dc.subject | Pyridines | en_US |
dc.subject | Silica Nanoparticles (SiNP) | en_US |
dc.title | Ball-Milling-Enabled Zn(OTf)2-Catalyzed Friedel–Crafts Hydroxyalkylation of Imidazo[1,2-a]pyridines and Indoles | en_US |
dc.type | Article | en_US |
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