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Electrochemical Oxidative Coupling Between Benzylic C(sp3)–H and N–H of Secondary Amines: Rapid Synthesis of α-Amino α-Aryl Esters

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dc.contributor.author Kumar, Indresh
dc.date.accessioned 2024-09-12T09:34:36Z
dc.date.available 2024-09-12T09:34:36Z
dc.date.issued 2021-06
dc.identifier.uri https://pubs.acs.org/doi/full/10.1021/acs.joc.1c00944
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/15552
dc.description.abstract An intermolecular electrochemical coupling between the benzylic C(sp3)–H bond and various secondary amines is reported. The electronic behavior of two electronically rich units viz the α-position of α-aryl acetates and amines was engineered electrochemically, thus facilitating their reactivity for the direct access of α-amino esters. A series of acyclic/cyclic secondary amines and α-aryl acetates were tested to furnish the corresponding α-amino esters with high yields (up to 92%) under mild conditions. en_US
dc.language.iso en en_US
dc.publisher ACS en_US
dc.subject Chemistry en_US
dc.subject Amines en_US
dc.subject Fossil fuels en_US
dc.subject Organic compounds en_US
dc.subject Purification en_US
dc.title Electrochemical Oxidative Coupling Between Benzylic C(sp3)–H and N–H of Secondary Amines: Rapid Synthesis of α-Amino α-Aryl Esters en_US
dc.type Article en_US


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