| dc.contributor.author |
Gaikwad, Anil Bhanudas |
|
| dc.date.accessioned |
2025-03-17T04:33:19Z |
|
| dc.date.available |
2025-03-17T04:33:19Z |
|
| dc.date.issued |
2024-08 |
|
| dc.identifier.uri |
https://onlinelibrary.wiley.com/doi/full/10.1111/fcp.13031 |
|
| dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/18381 |
|
| dc.description.abstract |
Being amongst the leading factors of death and distress, chronic kidney disease (CKD) has affected around 850 million people globally. The Wnt/β-catenin axis is vital for maintaining kidney homeostasis, from nephron generation to overall management. The β-catenin growth factor is typically not expressed in the adult kidney; however, its expression is found to increase under stress and injury conditions. It is categorised as canonical and non-canonical based on β-catenin availability, which mounts promising targets for ameliorating CKD. Hence, modulation of the Wnt/β-catenin signalling for CKD management is of utmost relevance. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
Wiley |
en_US |
| dc.subject |
Pharmacy |
en_US |
| dc.subject |
Chronic kidney disease (CKD) |
en_US |
| dc.subject |
Kidney homeostasis |
en_US |
| dc.title |
Wnt/beta-catenin modulation: A promising frontier in chronic kidney disease management |
en_US |
| dc.type |
Article |
en_US |