Reaction of Cob(i)alamin with Nitrous Oxide and Cob(in)alamin

Blackburn, Robert; Kyaw, Maung; Swallow, A. John

dc.contributor.author	Blackburn, Robert
dc.contributor.author	Kyaw, Maung
dc.contributor.author	Swallow, A. John
dc.date.accessioned	2025-04-09T11:22:17Z
dc.date.available	2025-04-09T11:22:17Z
dc.date.issued	1977
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/18606
dc.description.abstract	Cob(I)alamin (vitamin B12s) has been generated by pulse radiolysis of N2O-saturated solutions of cob(II)alamin (vitamin B12r) containing sodium formate. It reacts with N2O with rate constants in the range 200–1200 dm3 mol–1 s–1, depending on pH and buffer concentration. The final product is cob(II)alamin, formed in 100 % yield. The initial product is thought to be cob(III)alamin (vitamin B12a or B12h) but this does not build up to significant concentrations. Cob(III)alamin (vitamin B12a or B12h) reacts with cob(I)alamin with a rate constant of 3.2 × 107 dm3 mol–1 s–1 independent of pH in the range 5.8–11.0. Cyanocobalamin (vitamin B12) does not react with cob(I)alamin.	en_US
dc.language.iso	en	en_US
dc.publisher	Journal of the Chemical Society : Faraday Transaction - I. The Chemical Society, London. 1977, 73 (2)	en_US
dc.subject	Chemistry	en_US
dc.subject	Cob(i)alamin	en_US
dc.subject	Nitrous Oxide	en_US
dc.subject	Journal of the Chemical Society : Faraday Transaction - I	en_US
dc.title	Reaction of Cob(i)alamin with Nitrous Oxide and Cob(in)alamin	en_US
dc.type	Article	en_US