| dc.contributor.author |
Kumar, Anil |
|
| dc.date.accessioned |
2025-07-24T06:24:21Z |
|
| dc.date.available |
2025-07-24T06:24:21Z |
|
| dc.date.issued |
2025-01 |
|
| dc.identifier.uri |
https://pubs.acs.org/doi/10.1021/acs.joc.4c02335 |
|
| dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/19069 |
|
| dc.description.abstract |
A convenient and efficient transition-metal-free method has been developed for the C(sp2)–H alkoxylation/aryloxylation of 1,4-quinones by direct cross-dehydrogenative coupling with readily available alcohols and phenols in the presence of TEMPO under simple and mild conditions. The method allowed the installation of a wide range of alkoxy/aryloxy groups, exhibited high functional group tolerance, showed a broad substrate scope, afforded good to excellent yields of products in a simple one-pot operation, and could be performed on a gram scale. Mechanistic investigation indicated the involvement of the radical pathway. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
ACS |
en_US |
| dc.subject |
Chemistry |
en_US |
| dc.subject |
C(sp²)–H alkoxylation |
en_US |
| dc.subject |
Cross-dehydrogenative coupling (CDC) |
en_US |
| dc.subject |
Phenol coupling |
en_US |
| dc.subject |
Gram-scale synthesis |
en_US |
| dc.title |
Tempo-mediated direct C(SP2)–H alkoxylation/aryloxylation of 1,4-quinones |
en_US |
| dc.type |
Article |
en_US |