• Proteomics analysis in urinary bladder cancer patients identifies urinary SOD2 as a predictive marker of recurrence 

  Dubey, Uma S. (2021-12)

  Early non-invasive detection of tumor is an urgent clinical need for managing urothelial bladder cancer. Cystoscopy and cytology are the current standards for diagnosis of recurrence, but are limited by low sensitivity. ...
• Calcium chloride linked camel milk derived casein nanoparticles for the delivery of sorafenib in hepatocarcinoma cells 

  Dubey, Uma S. (Tech Science Press, 2021-09)

  Sorafenib, a multikinase inhibitor used for the treatment of hepatocellular carcinoma, is limited by its low oral bioavailability. To overcome this drawback, we have developed novel camel milk casein-derived nanoparticles ...
• Medicinal potential of Camel milk lactoferrin 

  Dubey, Uma S. (Intecopen, 2022)

  Camel milk is a rich source of protein with well-recognized medicinal properties to treat various diseases. The objective of this work is to understand the role of camel milk lactoferrin in immunomodulation and in disease ...
• Studies on cytotoxic activity of Camel milk whey protein as a nutraceutical against HeLa cells 

  Dubey, Uma S. (Camel Publishing House, 2023)

  Camel milk is an adapted dietary supplement with multiple antimicrobial and immuno-stimulatory properties. Diabetes, infant diarrhoea, hepatitis, allergy, lactose intolerance, and alcohol- induced liver damage have ...
• Aberrant expression of col14a1, celrs3, and cthrc1 in breast cancer сells 

  Dubey, Uma S. (Experimental oncology, 2023)

  Collagens, which are the major components of the extracellular matrix involved in the regulation of tumor microenvironment, could be differentially expressed in breast cancer (BC) with different transcriptome profiling. ...
• Evaluation of the cytotoxic activity of sorafenib-loaded camel milk casein nanoparticles against hepatocarcinoma cells 

  Dubey, Uma S. (Wiley, 2024-03)

  Sorafenib, a multikinase inhibitor is used to treat hepatocellular and renal carcinoma. However, a low solubility impedes its bioavailability and thus, effectiveness. This study aims to enhance its effectiveness by using ...
• Modeling the effect of vaccinations, hospital beds, and treatments on the dynamics of infectious disease with delayed optimal control and sensitivity analysis 

  Dubey, Uma S.; Dubey, Balram (Springer, 2024-08)

  Immunization plays a vital role in eradicating infectious diseases, typically requiring multiple doses at specific time intervals. This study focuses on developing and analyzing an infectious disease model governed by a ...
• Impact of chemo-immunotherapy on tumour-immune interactions: a non-autonomous model of tumor necrosis factor and T cell dynamics 

  Dubey, Uma S.; Dubey, Balram (2025)

  This study explores the interaction between cancer cells, helper T cells, cytotoxic T cells, and tumour necrosis factors in chemotherapy and immunotherapy treatment in the microenvironment [1]. The goal is to analyze the ...
• Bifurcation and chaotic dynamics in a spatiotemporal epidemic model with delayed optimal control, stochastic process, and sensitivity analysis 

  Dubey, Uma S.; Dubey, Balram (AIP, 2025-03)

  This study introduces an epidemic model with a Beddington–DeAngelis-type incidence rate and Holling type II treatment rate. The Bedding- ton–DeAngelis incidence rate is used to evaluate the effectiveness of inhibitory ...
• Evaluation of interleukin-33 & sST2 levels in type-2 diabetic mellitus patients with or without metabolic syndrome 

  Majumder, Syamantak (Indian Journal of Medical Research, 2023)

  Diabetes mellitus (DM) is characterized by increase in blood glucose levels due to defective insulin secretion or insulin sensitivity. Interleukins (ILs) are known to play an important role in the pathogenesis of DM. The ...
• Chloroquine attenuates hypoxia-mediated autophagy to curb thrombosis- an ex vivo and in vivo study 

  Mukherjee, Sudeshna; Majumder, Syamantak; Chowdhury, Shibasish; Chowdhury, Rajdeep (2024-04)

  Hypoxia can trigger the activation of blood platelets, leading to thrombosis. If not addressed clinically, it can cause severe complications and fatal consequences as well. The current treatment regime for thrombosis is ...
• 14K prolactin derived 14-mer antiangiogenic peptide targets bradykinin-/nitric oxide-cGMP-dependent angiogenesis 

  Majumder, Syamantak (FEBS Press, 2024-09)

  Over the past few decades, VEGF-targeted antiangiogenic therapy for cancers has gained increasing attention. Nevertheless, there are still several limitations such as the potential resistance mechanisms arising in cancer ...
• Metal-free, visible-light-mediated synthesis of tetracyclic benzimidazole: regioselective c–h functionalization with in vitro and computational study of anti-breast cancer compounds 

  Murugesan, Sankaranarayanan; Mukherjee, Sudeshna (ACS, 2025-02)

  Globally, breast cancer is the leading cause of mortality. Within the field of antibreast cancer drug design by several compound docking studies, eight new N-containing nonsteroid tetracyclic derivatives have been synthesized ...
• Plasmodium iron-sulfur [fe-s] Cluster assembly protein dre2 as a plausible target of artemisinin: mechanistic insights derived in a prokaryotic heterologous system 

  Saxena, Vishal; Garg, Shilpi (Elsevier, 2023-06)

  Iron-sulfur (Fe-S) cluster containing proteins have been assigned roles in various essential cellular processes, such as regulation of gene expression, electron transfer, sensing of oxygen and balancing free radical ...
• Midgut immune profiling and functional characterization of Aedes aegypti ABC transporter gene(s) using systemic and local bacterial challenges 

  Garg, Shilpi; Saxena, Vishal (Springer, 2025-01)

  The mosquito midgut is crucial for digestion and immune interactions. It produces several immune factors that protect the organ from invading pathogens and can limit their propagation. Studies on mosquito midgut transcriptome ...
• Formulating ternary inclusion complex of sorafenib tosylate using β-cyclodextrin and hydrophilic polymers: physicochemical characterization and in vitro assessment 

  Marathe, Sandhya Amol; Singhvi, Gautam (Springer, 2022-09)

  Sorafenib tosylate (SFNT) is the first-line drug for hepatocellular carcinoma. It exhibits poor solubility leading to low oral bioavailability subsequently requiring intake of large quantities of drug to exhibit desired ...
• Clustered regularly interspaced short palindromic repeats-cas system: diversity and regulation in enterobacteriaceae 

  Marathe, Sandhya Amol (Taylor & Francis, 2022-08)

  Insights into the arms race between bacteria and invading mobile genetic elements have revealed the intricacies of the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas system and the counter-defenses ...
• The Phylogenetic study of the CRISPR-Cas system in enterobacteriaceae 

  Unknown author (Springer, 2023-04)

  The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR-associated (Cas) system is a bacterial and archaeal adaptive immune system undergoing rapid multifaceted evolution. This evolution plausibly ...
• Comprehensive blueprint of Salmonella genomic plasticity identifies hotspots for pathogenicity genes 

  Marathe, Sandhya Amol (PLOS One, 2024-08)

  Understanding the dynamic evolution of Salmonella is vital for effective bacterial infection management. This study explores the role of the flexible genome, organised in regions of genomic plasticity (RGP), in shaping the ...
• Emerging relationship between the gut microbiota and neurodegenerative disorders 

  Marathe, Sandhya Amol; Tare, Meghana (Springer, 2024-08)

  A growing body of evidence indicates that the multitude of organisms residing in our gut can profoundly affect our health. These organisms are loosely termed as gut microbiota and have been known to affect the function as ...

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