A simple, efficient, and mild method for the synthesis of substituted 1,2,4-triazoles from hydrazines and formamide proceeds smoothly under microwave irradiation in the absence of a catalyst and shows excellent functional-group ...
An efficient and facile protocol has been developed for the synthesis of pyrazolo[1,5-a]pyrimidines through the tandem reaction of 3-aminopyrazoles and chalcones in the presence of catalytic amounts of KOH. The reported ...
An efficient one-pot sequential procedure is described for the synthesis of novel azole-fused quinazolines through Pd/Cu co-catalyzed, Ullmann-type coupling followed by cross dehydrogenative coupling of various azoles such ...
An efficient one-pot condensation reaction of imidazo[1,2-a]pyridine/pyrazolo[1,5-a] pyrimidines, aldehydes and acetamide has been investigated using Yb(OTf)3 as a catalyst in 1,4-dioxane. The reaction furnishes good to ...
A novel imidazolium salt-supported Mukaiyama reagent (2-chloropyridinium salt) has been developed and explored as an efficient coupling agent for amide bond formation. The use of an ionic liquid-supported reagent enabled ...
Advances in the last decade for the synthesis of the imidazo[1,2-a]pyridine scaffold from various substrates employing approaches such as multicomponent reactions, tandem processes, rearrangement reactions, inter- and ...
An efficient methodology for the synthesis of indole-fused dihydrothiopyrans has been developed from indoline-2-thiones. The protocol involves the synthesis of conjugated ene-yne-substituted indole-sulfides, a gold(III)-catalyzed ...
An efficient methodology has been developed for the synthesis of quinoxalin-2(1H)-one derivatives of 2-phenylimidazo[1,2-a]pyridines by microwave-irradiated Hinsberg heterocyclization between 2-phenylimidazo[1,2-a]pyridi ...
We report a facile iodine(III)-mediated synthesis of cyanoporphyrins and their DNA photocleavage activity. Cationic-porphyrin 9a showed intercalative binding towards DNA, whereas Zn(II)-cyanoporphyrinate 9b showed outside ...
An ionic liquid functionalized with benzyl azide was synthesized and its synthetic utility was evaluated by scavenging excess alkynes in the synthesis of 2,4-disubstituted quinoline via the Povarov reaction. The ionic ...
A simple and convenient approach is developed for the synthesis of the imidazo[1,2-f]phenanthridine framework via post-functionalization of imidazoles obtained through four-component reactions of 1,2-dicarbonyl compounds, ...
A metal-free, one-pot, iodine-mediated, microwave-assisted cyclization of 1-(1′-arylvinyl)-2-naphthols (ortho-vinylnaphthols) into 1-arylnaphthofurans is developed. The 1-arylnaphthofurans are isolated in good to excellent ...
A library of π-extended naptho-fused imidazo[1,2-a]pyridines were assembled by a copper-catalyzed cascade reaction using simple starting materials and mild reaction conditions. This protocol has high functional group ...
In(OTf)3 catalyzed microwave-assisted alkenylation of methoxyphenols was investigated. Exclusive formation of either indenes or chromenes was observed depending on the position of the methoxy group on phenol. The structures ...
An efficient and recyclable imidazolium-supported benzotriazole reagent (Im-CH2-BtH) as a novel synthetic auxiliary has been synthesized and its utility as a carboxyl group activating reagent via the formation of stable ...
The vanadium-catalyzed oxidative coupling of substituted 2-arylimidiazo[1,2-a]pyridines to N-methylmorpholine oxide, which acts as both a coupling partner and an oxidant, has been achieved. This reaction was applied to ...
Effect of ionic liquid (BMIM BF4) dispersion on Li+ ion oxide glass and glass-ceramics has been investigated. Addition of ionic liquid in a very small amount (0.5–5 wt.%) enhances the ionic conductivity significantly. For ...
Direct aerobic oxidative cross-dehydrogenative coupling of aryl acetaldehydes at C-3 position of imidazoheterocycles via copper catalyzed reaction resulted in the synthesis of dicarbonylated imidazoheterocycles in 55–85% ...
A simple and efficient one-pot protocol has been demonstrated for the synthesis of imidazo[1,2-c]quinazoline derivatives through a copper catalyzed tandem reaction between substituted 2-(2-bromophenyl)-1H-imidazoles and ...
A novel regioselective synthesis of 2-aminoquinolines and 2-arylquinoline-3-carbonitriles is described via copper-mediated tandem reaction. Formation of substituted quinolines involves Knoevenagel condensation of ...