Browsing Department of Pharmacy by Issue Date

Now showing items 1-20 of 772

Antioxidant properties of Indian medicinal plants

Jadhav, Hemant R. (Wiley, 2002-11)

The antioxidant properties of methanol extracts of 12 Indian medicinal plants, traditionally used in disease areas that probably involve free radical mechanisms, were evaluated by two methods, namely the DPPH (1,1-diphen ...
Pharmacophore Based Synthesis of 3-Chloroquinoxaline-2-carboxamides as Serotonin3 (5-HT3) Receptor Antagonist

Mahesh, R. (The Pharmaceutical Society of Japan, 2004)

A series of 3-chloroquinoxaline-2-carboxamides were designed and prepared by the condensation of 3-chloro-2-quinoxaloylchloride with appropriate Mannich bases of the p-aminophenol in the microwave environment. The synthesized ...
Microwave assisted synthesis of 2-(4-substituted piperazin-1-yl)-1,8-naphthyridine-3-carbonitrile as a new class of serotonin 5-HT3 receptor antagonists

Mahesh, R. (Elsevier, 2004-10)

A series of novel 2-(4-substituted piperazin-1-yl)-1,8-naphthyridine-3-carbonitrile 6 were prepared by microwave irradiation and conventional heating. The intermediate, 2-oxo-1,2-dihydro-1,8-naphthyridine-3-carbonitrile ...
Rationale for immunomodulatory and anti-inflammatory effects of Ocimum sanctum: radical scavenging potential and effect on nitric oxide production

Jadhav, Hemant R. (International Society for Horticultural Science, 2005)

Antioxidant activity of polar methanolic extract of aerial parts of Ocimum sanctum using multiple screens was studied. Various concentrations of the standardized extract were examined for the free radical scavenging activity, ...
Cancer chemotherapy-induced nausea and vomiting: role of mediators, development of drugs and treatment methods

Mahesh, R. (Avoxa, 2005-02)

The development of serotonin 5-HT3 receptor antagonists dramatically improved the treatment of chemotherapy-induced nausea and vomiting. Ondansetron, a serotonin 5-HT3 receptor antagonist in combination with dexamethasone ...
Cosmetic potential of herbal extracts

Jadhav, Hemant R. (NISCAIR, 2005-08)

Cosmetology, the science of alteration of appearance, has been practiced since primordial times. In India, the concept of using herbs for beautification finds its origin in traditional medicine literature like Ayurveda. ...
Current Advances in Antifungal Targets and Drug Development

Sundriyal, Sandeep (Bentham Science, 2006)

Fungi are one of the most neglected pathogens apparent from the fact that the Amphotericin B, a polyene antibiotic, discovered way back in 1956 is still used as a gold standard for antifungal therapy. Past two decades have ...
Molecular Electrostatic Potentials in the Design of Dendrimers for the Delivery of Glitazones

Sundriyal, Sandeep (American Scientific Publishers, 2006)

Glitazones are PPARγ agonistic insulin sensitizers used clinically for the treatment of type-2 diabetes. The delivery of these compounds with the help of dendrimers is possible. Ab initio MO calculations and MESP analysis ...
Synthesis and biological evaluation of a novel structural type of serotonin 5-HT3 receptor antagonists

Mahesh, R. (Elsevier, 2006-05)

A series of novel 3-substituted quinoxalin-2-carboxamides were designed as per the pharmacophoric requirement for 5-HT3 receptor antagonists and prepared by microwave irradiation and also by conventional method. The compounds ...
Modulating TNF-α signaling with natural products

Paul, Atish Tulshiram (Elsevier, 2006-08)

Natural products have been, and continue to be, a major source of pharmacologically active substances from which drugs can be developed. Currently, tumor necrosis factor-α (TNF-α) inhibitors from natural origins are being ...
Biodegradable Injectable In Situ Depot-Forming Drug Delivery Systems

Chitkara, Deepak (Wiley, 2006-11)

The scope of drug-delivery systems has expanded significantly in recent years providing new ways to deliver life saving therapeutics to patients. The development of new injectable drug-delivery systems has provided new ...
Modeling and Informatics in Designing Anti-Diabetic Agents

Sundriyal, Sandeep (Bentham Science, 2007)

Diabetes mellitus is a chronic metabolic disorder, characterized by glucose overproduction and glucose underutilization. Current therapy for T2DM includes drugs, like metformin, glitazones, sulphonyl ureas, etc. Extensive ...
Intermittent fasting prevents the progression of type I diabetic nephropathy in rats and changes the expression of Sir2 and p53

Gaikwad, Anil Bhanudas (Elsevier, 2007-03)

Diabetic nephropathy (DN) is one of the main causes of end stage renal disease (ESRD) and a leading cause of diabetes mellitus related morbidity and mortality. Recently, sirtuin are reported to have emerging pathogenetic ...
Differential effects of tannic acid on cisplatin induced nephrotoxicity in rats

Gaikwad, Anil Bhanudas (Elsevier, 2007-05)

Cisplatin is a widely used antineoplastic drug. Major drawback of cisplatin therapy is its nephrotoxicity. The objective of this study was to check the effect of tannic acid on cisplatin induced nephrotoxicity. Post-treatment ...
PPARγ agonists partially restores hyperglycemia induced aggravation of vascular dysfunction to angiotensin II in thoracic aorta isolated from rats with insulin resistance

Gaikwad, Anil Bhanudas (Elsevier, 2007-05)

Altered vascular responses to various vasopressors in animal models of insulin resistance (IR) and diabetes have been well documented. However, the precise mechanisms about vascular responses in IR with or without frank ...
In vitro hemolysis and lipid peroxidation-inducing activity of the tentacle extract of the sea anemone (Paracondylactis indicus Dave) in rat erythrocytes

Roy, Aniruddha (Wolters Kluwer, 2007-06)

In vitro hemolytic activity of the tentacle extract of Paracondylactis indicus (Dave), a sea anemone found in the eastern coastal region of West Bengal (India), was determined in rat erythrocytes
HPLC method for the determination of carboplatin and paclitaxel with cremophorEL in an amphiphilic polymer matrix

Chitkara, Deepak; Mittal, Anupama (Elsevier, 2007-08)

Simple and rapid reversed phase HPLC methods for individual as well as simultaneous analysis of paclitaxel and carboplatin with cremophorEL (CrEL) in an amphiphilic polymer matrix were developed. Different analytical ...
Evaluation of Proinflammatory Cytokine Pathway Inhibitors for p38 MAPK Inhibitory Potential

Paul, Atish Tulshiram (ACS, 2007-11)

The target for the anti-inflammatory natural products like amentoflavone (2), which act by interfering with the proinflammatory cytokine pathway (e.g., TNF-α, IL-1β, and NO synthase), is not yet well-defined. Data obtained ...
Metformin and glitazones: does similarity in biomolecular mechanism originate from tautomerism in these drugs?

Sundriyal, Sandeep (Wiley, 2007-11)

This theoretical study attempts to find out similarity between metformin and glitazone class of antidiabetic drugs. It was found that some tautomeric forms of both metformin and thiazolidinedione ring of glitazones have ...
Potential antidepressants: Pharmacology of 2-(4-methyl piperazin-1-yl)-1,8-naphthyridine-3-carbonitrile in rodent behavioural models

Mahesh, R. (Avoxa, 2007-12)

Now showing items 1-20 of 772

Search DSpace

Advanced Search

Browse

All of DSpace
This Collection
- By Issue Date
- Authors
- Titles
- Subjects

Browsing Department of Pharmacy by Issue Date

Browsing Department of Pharmacy by Issue Date

Search DSpace

Browse

All of DSpace

This Collection

My Account