Department of Pharmacy: Recent submissions

  • Self-Assembling, Amphiphilic Polymer–Gemcitabine Conjugate Shows Enhanced Antitumor Efficacy Against Human Pancreatic Adenocarcinoma 
    Chitkara, Deepak (ACS, 2013-06)
    The therapeutic efficacy of gemcitabine is severely compromised due to its rapid plasma metabolism. Moreover, its hydrophilicity poses a challenge for its efficient entrapment in nanosized delivery systems and to provide ...
  • Lipid-polymer hybrid nanocarriers for delivering cancer therapeutics 
    Chitkara, Deepak; Mittal, Anupama (Elsevier, 2018-02)
    Cancer remained a major cause of death providing diversified challenges in terms of treatment including non-specific toxicity, chemoresistance and relapse. Nanotechnology- based delivery systems grabbed tremendous attention ...
  • Biodegradable Injectable In Situ Depot-Forming Drug Delivery Systems 
    Chitkara, Deepak (Wiley, 2006-11)
    The scope of drug-delivery systems has expanded significantly in recent years providing new ways to deliver life saving therapeutics to patients. The development of new injectable drug-delivery systems has provided new ...
  • Chemoresistance in Prostate Cancer Cells Is Regulated by miRNAs and Hedgehog Pathway 
    Chitkara, Deepak (PLOS, 2012-06)
    Many prostate cancers relapse due to the generation of chemoresistance rendering first-line treatment drugs like paclitaxel (PTX) ineffective. The present study aims to determine the role of miRNAs and Hedgehog (Hh) pathway ...
  • Efficacy of gemcitabine conjugated and miRNA-205 complexed micelles for treatment of advanced pancreatic cancer 
    Chitkara, Deepak; Mittal, Anupama (Elsevier, 2014-08)
    Clinical effectiveness of gemcitabine in pancreatic cancer is hindered due to its rapid plasma metabolism and development of chemo-resistance. We have previously delineated the significant role of miRNAs in mediating the ...
  • Surface functionalization of exosomes for target-specific delivery and in vivo imaging & tracking: Strategies and significance 
    Chitkara, Deepak; Mittal, Anupama (Elsevier, 2020-10)
    Exosomes are natural nanovesicles excreted by many cells for intercellular communication and for transfer of materials including proteins, nucleic acids and even synthetic therapeutic agents. Surface modification of exosomes ...
  • Voices in Molecular Pharmaceutics: Meet Dr. Anil Jindal, Accomplished Educator and Drug Delivery Technologist 
    Jindal, Anil B. (ACS, 2023-01)
  • Pharmaceutical Process Engineering and Scale-up Principles 
    Jindal, Anil B. (Springer, 2023)
    The book offers a comprehensive overview of the unit operations involved in the manufacturing process of solid and liquid dosage forms, along with the scale-up of each operation. This book is a valuable resource for ...
  • Compression 
    Jindal, Anil B. (Springer, 2023-07)
    Compaction of powder involves compression and consolidation of the solids on the application of pressure. The forces involved in these processes play an important role in the design and development of solid oral dosage ...
  • Pan Coating 
    Jindal, Anil B. (Springer, 2023-07)
    Coating a tablet provides different features to the dosage form. Pan coating is the traditional method for film, enteric, or sugar coating of tablets. The coating process is dependent upon the advances in the techniques, ...
  • Properties of Solids 
    Jindal, Anil B. (Springer, 2023-07)
    Properties of solids, including particle size, particle size distribution, particle shape, particle density, surface area, porosity, surface charge, flow, and cohesiveness, play a significant role during the processing of ...
  • Fluid Bed Processing Technology 
    Jindal, Anil B. (Springer, 2023-07)
    Fluid bed processing technology is widely used in the pharmaceutical industry for the processing of multiparticulates. The chapter describes the theory of fluidization followed by the components of a fluidized bed processor ...
  • Size Reduction 
    Jindal, Anil B. (Springer, 2023-07)
    Size reduction refers to the process of the formation of small particles with a large surface area. The stress-strain curve of the material determines the energy needed for size reduction with a desirable particle size ...
  • Drying 
    Jindal, Anil B. (Springer, 2023-07)
    Drying is a vital process in pharmaceutical formulation involving removal of moisture from solids by applying heat, thus resulting in both heat and mass transfer. The process when theoretically studied utilizes various ...
  • Manufacturing and Scale-Up of Biotechnology-Derived Products 
    Jindal, Anil B. (Springer, 2023-07)
    In the last decade, there has been a notable increase in the approval of biotechnology-based pharmaceutical products by regulatory agencies for treating various diseases. Large-scale production of these products is crucial ...
  • Scale-Up of Liquid Mixing Process 
    Jindal, Anil B. (Springer, 2023-07)
    To meet the growing demands of production and reduce costs, it is necessary to increase the scale of production. However, transferring the lab-scale process to a large manufacturing scale can be a challenging task for ...
  • Mixing 
    Jindal, Anil B. (Springer, 2023-07)
    Mixing is an important process in the pharmaceutical industry; it ensures the uniformity of composition among all components by blending them; it is a vital step to achieve dose uniformity. To achieve optimal mixing, factors ...
  • Nanocarrier based active targeting strategies against erythrocytic stage of malaria 
    Jindal, Anil B. (Elsevier, 2023-10)
    The Global Technical Strategy for Malaria 2016–2030 aims to achieve a 90% reduction in malaria cases, and strategic planning and execution are crucial for accomplishing this target. This review aims to understand the complex ...
  • Nanomedicines for the Treatment of Veterinary Parasitic Infections 
    Jindal, Anil B. (Springer, 2023-11)
    Negligence in treating veterinary parasitic infection (VPI) has caused 50% of livestock loss as per the World Organization for Animal Health (WOAH). Only five major companies, including Zoetis, MSD AH, Elanco, Boehringer ...
  • Nanomedicines for the Treatment of Trypanosomiasis 
    Jindal, Anil B. (Springer, 2023-11)
    Trypanosomiasis is a neglected tropical disease that is mainly prevalent in low- and middle-income countries including regions of Africa, Asia, and America. Except for fexinidazole which was discovered in late 2018, no new ...

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