Department of Pharmacy: Recent submissions

Now showing items 321-340 of 772

Freeze-drying revolution: unleashing the potential of lyophilization in advancing drug delivery systems

Jindal, Anil B. (Springer, 2023-11)

Lyophilization also known as freeze-drying is a technique that has been employed to enhance the long-term durability of nanoparticles (NPs) that are utilized for drug delivery applications. This method is used to prevent ...
Precise Fabrication of Ocular Inserts Using an Innovative Laser-Driven CaliCut Technology: In Vitro and in Vivo Evaluation

Jindal, Anil B. (Elsevier, 2023-12)

Ocular inserts offer distinct advantages, including a preservative-free drug delivery system, the ability to provide tailored drug release, and ease of administration. The present research paper delves into the development ...
Long-acting therapeutics: development strategies and clinical significance

Jindal, Anil B. (Elsevier, 2023-12)

High dosing frequency poses a considerable challenge in treating chronic conditions. This often results in missed doses, ultimately leading to therapy failure. Formulations capable of maintaining a prolonged plasma drug ...
Bugs as Drugs: Understanding the Linkage between Gut Microbiota and Cancer Treatment

Jindal, Anil B. (Bentham Science, 2022)

The commensal microbiota is known to regulate host physiology. Dysbiosis or compromised resilience in the microbial ecology is related to the impending risk of cancer. A potential link between cancer and microbiota is ...
Current status of dolutegravir delivery systems for the treatment of HIV-1 infection

Jindal, Anil B. (Elsevier, 2022-10)

According to the World Health Organization (WHO), an estimated 37.7 million people were living with HIV in 2020. Dolutegravir is recommended as the first line and second line antiretroviral drug for the treatment of HIV-1 ...
Recent Advances in Teriparatide Delivery by-virtue-of Novel Drug Delivery Approaches for the Management of Osteoporosis

Jindal, Anil B. (Begell House, 2023)

Osteoporosis is a bone incapacitating malady which globally accounts for over hundred million fractures annually. Therapeutic interventions for management of osteoporosis are divided as antiresorptive agents and osteoanabolic ...
Evaluation of Pharmacokinetics, Biodistribution, and Antimalarial Efficacy of Artemether-Loaded Polymeric Nanorods

Jindal, Anil B. (ACS, 2023)

Artemether oily injection is recommended for the treatment of severe malaria by the intramuscular route. The major limitations of the artemisinin combination therapy are erratic absorption from the injection site and high ...
Lipid Based Nanocarriers for Delivery of Anti-HIV Drugs: A Mini Review

Jindal, Anil B. (Bentham Science, 2018)

Introduction: At the end of 2014, almost 36.9 million people were living with HIV which has put the HIV infection in the list of major public health issues. Although almost thirty drugs are available for the treatment of ...
Intracellular Delivery: An Overview

Jindal, Anil B. (Springer, 2019-11)

Targeted intracellular delivery is gaining importance, especially for improved therapy of cancer and intracellular infections. Endocytosis or cellular internalization, a physiological process for intracellular delivery of ...
Recent Progress in Hot Melt Extrusion Technology in Pharmaceutical Dosage Form Design

Jindal, Anil B. (Bentham Science, 2022-09)

The Hot Melt Extrusion (HME) technique has shown tremendous potential in transforming highly hydrophobic crystalline drug substances into amorphous solids without using solvents. This review explores in detail the general ...
Intranasal transmucosal drug delivery: An alternative approach to the parenteral route for medical emergencies

Jindal, Anil B. (Elsevier, 2023-05)

Medical emergencies such as insulin-induced hypoglycaemia, anaphylactic reactions, seizures and opioid induced respiratory depression, need to be treated as quickly as possible in order to prevent untoward life-threatening ...
A sensitive RP-HPLC method for estimation of artemether from polymeric nanoparticles after pre-column acid treatment using UV-visible detector

Jindal, Anil B. (Taylor & Francis, 2020-06)

Artemether; a sesquiterpene lactone is widely used for the treatment of malaria as artemisinin-based combination therapy (ACT). The present work involves the development and validation of sensitive reversed-phase ...
Packaging of Non-Injectable Liquid Pharmaceuticals: A Review

Jindal, Anil B. (JAPS, 2017-02)

Stability of the pharmaceutical product is strongly influenced by the type and material of packaging, thereby it is gaining substantial attention during the formulation development. Selection of suitable packaging material ...
Development of cationic Isometamidium chloride loaded long-acting lipid nanoformulation: optimization, cellular uptake, pharmacokinetics, biodistribution, and immunohistochemical evaluation

Jindal, Anil B. (Elsevier, 2021-12)

The aim of the present work involved the development and evaluation of long-acting Isometamidium chloride (ISMM)-Docusate sodium (DS) complex loaded lipid nanoparticles (LA ISMM-DS LNP). The development involved screening ...
Long-acting parenteral drug delivery systems for the treatment of chronic diseases

Jindal, Anil B. (Elsevier, 2023-07)

The management of chronic conditions often requires patients to take daily medication for an extended duration. However, the need for daily dosing can lead to nonadherence to the therapy, which can result in the recurrence ...
An insight into obtaining of non-spherical particles by mechanical stretching of micro- and nanospheres

Jindal, Anil B. (Elsevier, 2020-10)

Drug encapsulated nanoparticles offer several advantages, including site-specific delivery, improved solubility, stability, bioavailability with reduced toxicity. Besides the particle size, the shape of the particles also ...
Fabrication and evaluation of artemether loaded polymeric nanorods obtained by mechanical stretching of nanospheres

Jindal, Anil B. (Elsevier, 2021-08)

The objective of the present study was to prepare and evaluate artemether-loaded poly (lactic-co-glycolic acid) (PLGA) nanorods by mechanical stretching of nanospheres. Artemether-loaded PLGA nanospheres were prepared by ...
Long-Acting Efavirenz and HIV-1 Fusion Inhibitor Peptide Co-loaded Polymer–Lipid Hybrid Nanoparticles: Statistical Optimization, Cellular Uptake, and In Vivo Biodistribution

Jindal, Anil B. (ACS, 2020-08)

The objective of the present study was to develop long-acting efavirenz (Efa)–enfuvirtide (Enf) Co-loaded polymer–lipid hybrid nanoparticles (PLN) with improved intracellular delivery to target T-cells and macrophage cells ...
Asymmetric lipid–polymer particles (LIPOMER) by modified nanoprecipitation: role of non-solvent composition

Jindal, Anil B. (Elsevier, 2015-07)

Asymmetric lipid polymer nanostructures (LIPOMER) comprising glyceryl monostearate (GMS) as lipid and Gantrez AN 119 (Gantrez) as polymer, revealed enhanced splenic accumulation. In the present paper, we attempt to explain ...
Development and validation of reverse-phase high-performance liquid chromatographic (RP-HPLC) method for quantification of Efavirenz in Efavirenz-Enfuvirtide co-loaded polymer-lipid hybrid nanoparticles

Jindal, Anil B. (Elsevier, 2019-10)

The objective of present work was to develop rapid, sensitive, selective, accurate and precise RP-HPLC method for analysis of Efavirenz from combination anti-HIV drug (Efavirenz-Enfuvirtide) incorporated into polymer-lipid ...

Now showing items 321-340 of 772

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