The use of perfumes in everyday life has become quintessential for aesthetic effects, with an increased demand in several markets such as food industries, cosmetics, and toiletries. The aroma present in perfumes is obtained ...

Numerous epidemiological studies have demonstrated that insulin resistance contributes to Alzheimer's disease (AD) pathogenesis. However the molecular mechanisms is still remain elusive but various studies have highlighted ...

Diabetes mellitus is a complicated metabolic disorder associated with various vascular complications, and these complications lead to co-morbid diseases such as Alzheimer's. Repaglinide, inhibits the ATP-sensitive potassium ...

Type-2 Diabetes Mellitus and insulin resistance increases the risk of Alzheimer’s disease (AD). Recent studies highlighted the role of peroxisome proliferator-activated receptor-gamma (PPAR-γ) in modulation of AD. This ...

Antibody–drug conjugates (ADCs) are relatively newly developed treatments but rapidly growing science. Theoretically, they are like a combination of payload (the drug that is to be delivered; often cytotoxic) and targeted ...

Gonadotropin-releasing hormone (GnRH) is the primary regulator of the mammalian reproductive axis. We investigated the spatiotemporal expression of GnRH splice variants (V1, V2, and V3) and splicing factors (Srsf7, Srsf9, ...

Diabetes Mellitus is a metabolic disorder characterized by insulin resistance with several metabolic abnormalities which trigger neuronal complications, neurodegeneration, and cognitive impairments. Repaglinide (REP) is ...

Metabolic syndrome (MS) includes clusters of metabolic disorders and type 2 DM (T2DM) is most common MS which cause insulin resistance (IR). The IR mediated dysregulation of signaling cascades in brain increase the production ...

Alzheimer's disease (AD) is characterized by the progressive deposition of fibrillar amyloid-β (Aβ) in the form of extracellular plaques and hyperphosphorylated tau as intraneuronal neuro fibrillary tangles (NFTs). Studies ...

Endocrine-disrupting chemicals (EDCs) are xenobiotics that disrupt the endocrine system in humans at ecologically significant concentrations. Various substances are exposed to human health via routes including food, water, ...