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DRP1-mediated mitochondrial dynamics orchestrate EMT in glioblastoma cells

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dc.contributor.author Chowdhury, Shibasish
dc.contributor.author Chowdhury, Rajdeep
dc.contributor.author Mukherjee, Sudeshna
dc.date.accessioned 2026-01-08T11:23:31Z
dc.date.available 2026-01-08T11:23:31Z
dc.date.issued 2025-12
dc.identifier.uri https://www.biorxiv.org/content/10.64898/2025.12.12.694080v1.abstract
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/20506
dc.description.abstract Epithelial to mesenchymal transition (EMT), a differentiation process, frequently imparts invasive properties in Glioblastoma Multiforme (GBM), which leads to a poor prognosis. Cells lose apical-basal polarity, cell-cell connections, and/or chemo-resistance during EMT, which can result in the spread of cancer and the acquisition of additional stem cell-like traits. It is unclear how organelle dynamics influence EMT in this respect. The interaction between cytoskeletal and mitochondrial regulators governing GBM cell EMT is explored in this article. en_US
dc.language.iso en en_US
dc.subject Biology en_US
dc.subject Epithelial–mesenchymal transition (EMT) en_US
dc.subject Glioblastoma multiforme (GBM) en_US
dc.subject Mitochondrial dynamics en_US
dc.subject Cytoskeletal regulation en_US
dc.title DRP1-mediated mitochondrial dynamics orchestrate EMT in glioblastoma cells en_US
dc.type Article en_US


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