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Inherent weakly coordinating oxo-group-directed ruthenium(ii)-catalyzed C5 functionalization of 2-arylquinolin-4(1h)-ones

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dc.contributor.author Kumar, Anil
dc.date.accessioned 2026-01-19T09:32:09Z
dc.date.available 2026-01-19T09:32:09Z
dc.date.issued 2025
dc.identifier.uri https://pubs.acs.org/doi/full/10.1021/acs.orglett.5c02418
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/20579
dc.description.abstract A Ru(II)-catalyzed inherent weakly coordinating oxo-group-directed site-selective C5 functionalization of 2-arylquinolin-4(1H)-ones using various coupling partners like allyl alcohols, acrylates, styrenes, maleimides, and acrylamide has been described. The developed method allowed the synthesis of C5-substituted 2-arylquinolin-4(1H)-ones in good to excellent yields. The protocol is compatible with a broad range of functional groups and can be used on the gram scale. In addition, based on the control experiments, a plausible reaction mechanism has been proposed for this transformation. en_US
dc.language.iso en en_US
dc.publisher ACS en_US
dc.subject Chemistry en_US
dc.subject Ru(II) catalysis en_US
dc.subject C5 functionalization en_US
dc.subject Quinolinone derivatives en_US
dc.subject Site-selective coupling en_US
dc.title Inherent weakly coordinating oxo-group-directed ruthenium(ii)-catalyzed C5 functionalization of 2-arylquinolin-4(1h)-ones en_US
dc.type Article en_US


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