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Organocatalytic [4+2] Benzannulation between 1,4-dithiane-based enal and nitroolefins to access 2-nitrobiaryls

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dc.contributor.author Kumar, Indresh
dc.date.accessioned 2026-01-22T09:16:48Z
dc.date.available 2026-01-22T09:16:48Z
dc.date.issued 2025-01
dc.identifier.uri https://aces.onlinelibrary.wiley.com/doi/10.1002/asia.202401408?af=R
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/20617
dc.description.abstract A simple method for constructing unsymmetrical 2-nitrobiaryls has been developed between substituted 1,4-dithiine-2-carbaldehyde and nitroolefins under metal-free conditions. To gain the advantage of the HOMO-raising effect of temporary substitutions on in situ generated dienamine intermediate, the present protocol established [4+2] benzannulation of 1,4-dithiane-tethered enals with nitroolefin. Further, easy unmasking of 1,4-dithiine units results in a benzannulation product like that of unsubstituted enals, which are difficult to access. Several 2-nitrobiaryls have been accessed with moderate to good yields and with promising synthetic applications. en_US
dc.language.iso en en_US
dc.publisher Wiley en_US
dc.subject Chemistry en_US
dc.subject Unsymmetrical 2-nitrobiaryls en_US
dc.subject Metal-free benzannulation en_US
dc.subject Nitroolefin coupling en_US
dc.subject Dienamine intermediate en_US
dc.title Organocatalytic [4+2] Benzannulation between 1,4-dithiane-based enal and nitroolefins to access 2-nitrobiaryls en_US
dc.type Article en_US


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