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Switchable regioselective hydroalkylation of 2-arylindoles with maleimides

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dc.contributor.author Kumar, Anil
dc.date.accessioned 2021-10-14T13:09:21Z
dc.date.available 2021-10-14T13:09:21Z
dc.date.issued 2021
dc.identifier.uri https://pubs.rsc.org/en/content/articlelanding/2021/ob/d1ob00690h
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2805
dc.description.abstract A condition-based switchable regioselective hydroalkylation of 2-arylindoles with maleimides has been developed. The reaction in the presence of a Ru(II)-catalyst resulted in hydroalkylation at the ortho-position of the C2-aryl ring via C–H activation whereas the reaction in the absence of the catalyst in TFE resulted in C3-hydroalkylation. Various functional groups both on the indole ring and on the 2-phenyl ring were tolerated and a wide range of hydroalkylated products were obtained in moderate to high (37–88%) yields. en_US
dc.language.iso en en_US
dc.publisher RSC en_US
dc.subject Chemistry en_US
dc.subject Hydroalkylation en_US
dc.subject Maleimides en_US
dc.title Switchable regioselective hydroalkylation of 2-arylindoles with maleimides en_US
dc.type Article en_US


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