dc.contributor.author |
Kumar, Anil |
|
dc.date.accessioned |
2021-10-14T13:09:24Z |
|
dc.date.available |
2021-10-14T13:09:24Z |
|
dc.date.issued |
2021 |
|
dc.identifier.uri |
https://pubs.acs.org/doi/abs/10.1021/acs.orglett.1c00031 |
|
dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2806 |
|
dc.description.abstract |
A simple and highly efficient metal-free method has been developed for hydroxyfluoroalkylation of indoles and imidazo[1,2-a]pyridines via TEMPO-mediated C(sp3)–H and C(sp2)–H bond cross-dehydrogenative coupling of fluorinated alcohols and indoles. The protocol showed broad substrate scope, afforded good yields of hydroxyfluoroalkylated products, and was amenable for scale-up. Mechanistic investigation indicated involvement of the radical pathway. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
ACS |
en_US |
dc.subject |
Chemistry |
en_US |
dc.subject |
Functionalization |
en_US |
dc.subject |
Indoles |
en_US |
dc.subject |
Chemical reactions |
en_US |
dc.title |
TEMPO-Mediated Cross-Dehydrogenative Coupling of Indoles and Imidazo[1,2-a]pyridines with Fluorinated Alcohols |
en_US |
dc.type |
Article |
en_US |