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Metal-free benzoylation of imidazoheterocycles by oxidative decarboxylation of arylglyoxylic acids

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dc.contributor.author Kumar, Anil
dc.date.accessioned 2021-10-14T13:09:52Z
dc.date.available 2021-10-14T13:09:52Z
dc.date.issued 2020
dc.identifier.uri https://pubs.rsc.org/en/content/articlelanding/2020/ob/d0ob01842b
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2811
dc.description.abstract A simple and straightforward approach has been realized for the direct benzoylation of imidazoheterocycles by oxidative decarboxylation of arylglyoxylic acids in the presence of K2S2O8 as an oxidant. Various functional groups were tolerated on both imidazoheterocycles and arylglyoxylic acids and a wide range of C5-benzoyl-imidazoheterocycles were obtained in good to high yields (50–84%). Radical trapping experiments confirmed the involvement of the radical pathway. The developed protocol is amenable for a scale-up reaction. en_US
dc.language.iso en en_US
dc.publisher RSC en_US
dc.subject Chemistry en_US
dc.subject Benzoylation en_US
dc.subject Imidazoheterocycles en_US
dc.subject Arylglyoxylic acids en_US
dc.title Metal-free benzoylation of imidazoheterocycles by oxidative decarboxylation of arylglyoxylic acids en_US
dc.type Article en_US


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