| dc.contributor.author |
Kumar, Anil |
|
| dc.date.accessioned |
2021-10-14T13:10:04Z |
|
| dc.date.available |
2021-10-14T13:10:04Z |
|
| dc.date.issued |
2020 |
|
| dc.identifier.uri |
https://pubag.nal.usda.gov/catalog/7074024 |
|
| dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2814 |
|
| dc.description.abstract |
A simple and facile method for the synthesis of 3-(arylthio)imidazo[1,2-a]pyridin-2-ols has been developed by a KOH-mediated reaction of 2-aminopyridinium bromides with aryl thiols. The method afforded a wide range of 3-(arylthio)imidazo[1,2-a]pyridin-2-ols in moderate to excellent (56–95%) yields with excellent functional group tolerance. Synthetic utility of the protocol was demonstrated by gram-scale reaction and preparation of 2-aryl-3-(p-tolylthio)imidazo[1,2-a]pyridines from 3-(p-tolylthio)imidazo[1,2-a]pyridin-2-ol. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
USDA |
en_US |
| dc.subject |
Chemistry |
en_US |
| dc.subject |
Bromides |
en_US |
| dc.subject |
Methodology |
en_US |
| dc.subject |
Pyridines |
en_US |
| dc.subject |
Thiols |
en_US |
| dc.subject |
Utilities |
en_US |
| dc.title |
KOH-mediated intramolecular amidation and sulfenylation: A direct approach to access 3-(arylthio)imidazo[1,2-a]pyridin-2-ols |
en_US |
| dc.type |
Article |
en_US |