| dc.contributor.author |
Kumar, Anil |
|
| dc.date.accessioned |
2021-10-14T13:10:55Z |
|
| dc.date.available |
2021-10-14T13:10:55Z |
|
| dc.date.issued |
2019 |
|
| dc.identifier.uri |
https://pubs.rsc.org/en/content/articlelanding/2019/ob/c9ob00440h |
|
| dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2821 |
|
| dc.description.abstract |
A highly efficient protocol has been developed for the synthesis of diversely substituted isoindolo[2,1-b]isoquinolin-7(5H)-ones through sequential Cu(II)-catalyzed Sonogashira coupling, intramolecular hydroamidation followed by palladium-catalyzed ligand-free Heck reaction. Good to excellent yields (41–94%) were observed with excellent substrate scope and functional group tolerance. The developed method represents a practical strategy for the construction of bioactive isoindolo[2,1-b]isoquinolin-7(5H)-ones. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
RSC |
en_US |
| dc.subject |
Chemistry |
en_US |
| dc.subject |
Copper |
en_US |
| dc.subject |
Palladium-catalyzed |
en_US |
| dc.subject |
Isoindolo |
en_US |
| dc.title |
Copper and palladium-catalyzed sequential reactions: one-pot synthesis of isoindolo[2,1-b]isoquinolin-7(5H)-ones |
en_US |
| dc.type |
Article |
en_US |