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Sequential Copper-Catalyzed Sonogashira Coupling, Hydroamination and Palladium-Catalyzed Intramolecular Direct Arylation: Synthesis of Azepino-Fused Isoindolinones

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dc.contributor.author Kumar, Anil
dc.date.accessioned 2021-10-14T13:11:25Z
dc.date.available 2021-10-14T13:11:25Z
dc.date.issued 2017-11-09
dc.identifier.uri https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.201701379
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2829
dc.description.abstract A modular synthesis of azepino-fused isoindolinones has been developed in form of a sequential copper- and palladium-catalyzed tandem reaction. The developed protocol involved the formation of one carbon–nitrogen and two carbon–carbon bonds in a one-pot fashion. The palladium-catalyzed intramolecular direct-arylation step involves the formation of an unusual eight-membered palladacycle. en_US
dc.language.iso en en_US
dc.publisher Wiley en_US
dc.subject Chemistry en_US
dc.subject Copper-Catalyzed en_US
dc.subject Sonogashira Coupling en_US
dc.subject Azepino-Fused Isoindolinones en_US
dc.title Sequential Copper-Catalyzed Sonogashira Coupling, Hydroamination and Palladium-Catalyzed Intramolecular Direct Arylation: Synthesis of Azepino-Fused Isoindolinones en_US
dc.type Article en_US


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