| dc.contributor.author |
Kumar, Anil |
|
| dc.contributor.author |
Kumar, Dalip |
|
| dc.date.accessioned |
2021-10-14T13:11:33Z |
|
| dc.date.available |
2021-10-14T13:11:33Z |
|
| dc.date.issued |
2021-11-25 |
|
| dc.identifier.uri |
https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/slct.201702025 |
|
| dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2831 |
|
| dc.description.abstract |
A one-pot, atom-economical multicomponent reaction of 2-bromoindole-3-carbaldehydes, alkynes and ammonia was developed in the presence of copper catalyst for the synthesis of a series of 3-aryl-γ−carboline derivatives in good to high yields. The developed reaction involved formation of imine followed by copper-catalyzed directed Sonogashira coupling and intramolecular hydroamination sequence of reactions. This multicomponent approach features mild reaction conditions and good functional group tolerance to access variety of 3-aryl γ-carbolines. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
Wiley |
en_US |
| dc.subject |
Chemistry |
en_US |
| dc.subject |
Copper-Catalyzed |
en_US |
| dc.subject |
Sonogashira Coupling |
en_US |
| dc.subject |
Intramolecular Hydroamination |
en_US |
| dc.title |
Copper-Catalyzed Tandem Imine Formation, Sonogashira Coupling and Intramolecular Hydroamination: A Facile Synthesis of 3-Aryl-γ−carbolines |
en_US |
| dc.type |
Article |
en_US |