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A Facile Synthesis of Quinazolin-4(3H)-ones via Copper-Catalyzed One-Pot, Three-Component Tandem Reaction

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dc.contributor.author Kumar, Anil
dc.contributor.author Kumar, Dalip
dc.date.accessioned 2021-10-14T13:12:12Z
dc.date.available 2021-10-14T13:12:12Z
dc.date.issued 2017-09-13
dc.identifier.uri https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.201701778
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2832
dc.description.abstract A simple and convenient one-pot, three-component tandem reaction has been developed for the synthesis of substituted quinazolin-4(3H)-ones using CuI/L-proline as catalytic system. A series of 35 quinazolin-4(3H)-ones was synthesized in good to high yield. The method involves copper-catalyzed double C−N coupling, reductive amination, condensation, cyclization and aerobic oxidation. Good functional group tolerance, mild reaction condition, readily available starting materials and user friendly procedure makes this protocol practically good and attractive method for the synthesis of quinazolin-4(3H)-ones. en_US
dc.language.iso en en_US
dc.publisher Wiley en_US
dc.subject Chemistry en_US
dc.subject Facile Synthesis en_US
dc.subject Copper-Catalyzed en_US
dc.title A Facile Synthesis of Quinazolin-4(3H)-ones via Copper-Catalyzed One-Pot, Three-Component Tandem Reaction en_US
dc.type Article en_US


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