dc.contributor.author |
Kumar, Anil |
|
dc.contributor.author |
Sakhuja, Rajeev |
|
dc.date.accessioned |
2021-10-14T13:12:56Z |
|
dc.date.available |
2021-10-14T13:12:56Z |
|
dc.date.issued |
2016 |
|
dc.identifier.uri |
https://pubs.acs.org/doi/abs/10.1021/acs.joc.6b02282 |
|
dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2841 |
|
dc.description.abstract |
Direct ortho amidation at the phenyl ring of 2-phenylimidazo heterocycles with aryl isocyanates has been achieved via a chelation-assisted cationic ruthenium(II) complex catalyzed mechanism. The methodology provides a straightforward, high-yielding regioselective approach toward the synthesis of an array of ortho-amidated phenylimidazo heterocycles without prior activation of C(sp2)–H. This also reports the first method for coupling of aryl isocyanates with the imidazo[1,2-a]pyridine system via a pentacyclometalated intermediate. The methodology is found to be easily scalable and could be applied toward the selective ortho amidation of 2-heteroarylimidazo[1,2-a]pyridine frameworks. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
ACS |
en_US |
dc.subject |
Chemistry |
en_US |
dc.subject |
Catalysts |
en_US |
dc.subject |
Hydrocarbons |
en_US |
dc.subject |
Organic reactions |
en_US |
dc.title |
Ruthenium(II)-Catalyzed Regioselective Ortho Amidation of Imidazo Heterocycles with Isocyanates |
en_US |
dc.type |
Article |
en_US |