dc.contributor.author |
Kumar, Anil |
|
dc.date.accessioned |
2021-10-17T13:57:18Z |
|
dc.date.available |
2021-10-17T13:57:18Z |
|
dc.date.issued |
2015 |
|
dc.identifier.uri |
https://pubs.rsc.org/en/content/articlelanding/2015/ra/c4ra13056a |
|
dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2870 |
|
dc.description.abstract |
A facile synthesis of 3-aroylimidazo[1,2-a]pyridine derivatives has been achieved through the one-pot, three-component tandem reaction of acetophenones, arylaldehydes and 2-aminopyridines in the presence of a catalytic amount of copper(II) chloride and air as the sole oxidant. The developed one-pot method is atom-economical and utilizes readily available precursors to offer highly functionalized N-fused imidazoles in moderate to good yields (26–82%). The presented tandem process is expected to proceed via crossed aldol condensation, Michael addition, copper catalyzed oxidative cyclization and subsequent aromatization. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
RSC |
en_US |
dc.subject |
Chemistry |
en_US |
dc.subject |
3-aroylimidazo |
en_US |
dc.subject |
2-aminopyridines |
en_US |
dc.title |
One-pot, three component tandem reaction of 2-aminopyridines, acetophenones and aldehydes: synthesis of 3-aroylimidazo[1,2-a]pyridines |
en_US |
dc.type |
Article |
en_US |